http://www.bing.com:80/search?q=XCT+Spatial+Resolution+GraphSearch resultshttp://www.bing.com:80/s/a/rsslogo.gifhttp://www.bing.com:80/search?q=XCT+Spatial+Resolution+GraphCopyright © 2026 Microsoft. All rights reserved. These XML results may not be used, reproduced or transmitted in any manner or for any purpose other than rendering Bing results within an RSS aggregator for your personal, non-commercial use. Any other use of these results requires express written permission from Microsoft Corporation. By accessing this web page or using these results in any manner whatsoever, you agree to be bound by the foregoing restrictions.https://en.m.wikipedia.org/wiki/Cystine/glutamate_transporterThe SLC7A11 gene encodes a sodium-independent cystine - glutamate antiporter that is chloride dependent, also known as xCT. Along with a heavy chain subunit from SLC3A2, the SLC7A11 light chain comprises system Xc-, which is the functional cystine-glutamate antiporter.Sat, 06 Jun 2026 02:13:00 GMThttps://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(20)30457-3In recent years, the xCT molecule has been found to play an important role in tumor growth, progression, metastasis, and multidrug resistance in various types of cancer. Interestingly, xCT also exhibits an essential function in regulating tumor-associated ferroptosis.Sat, 29 Nov 2025 19:54:00 GMThttps://academic.oup.com/proteincell/article/12/8/599/6724511The cystine/glutamate antiporter SLC7A11 (also commonly known as xCT) functions to import cystine for glutathione biosynthesis and antioxidant defense and is overexpressed in multiple human cancers.Wed, 03 Jun 2026 01:40:00 GMThttps://www.nature.com/articles/s41467-023-39401-9The cystine transporter solute carrier family 7 member 11 (SLC7A11; also called xCT) protects cancer cells from oxidative stress and is overexpressed in many cancers.Tue, 20 Jun 2023 23:57:00 GMThttps://pmc.ncbi.nlm.nih.gov/articles/PMC4333839/Expression of xCT, a component of the xc– amino-acid transporter, is essential for the uptake of cystine required for intracellular glutathione (GSH) synthesis and maintenance of the intracellular redox balance.Mon, 17 Feb 2025 14:05:00 GMThttps://link.springer.com/article/10.1007/s11064-026-04776-wThis antiporter is composed of two subunits: xCT (encoded by the gene Slc7a11) and a heavy chain, CD98 (encoded by the gene Slc3a2). xCT is the subunit responsible for cystine/glutamate transport, while CD98 is responsible for the translocation of system X c− to the membrane.Sat, 06 Jun 2026 16:53:00 GMThttps://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.858462/fullSLC7A11/xCT is an antiporter that mediates the uptake of extracellular cystine in exchange for glutamate. Cystine is reduced to cysteine, which is a rate-lim...Tue, 22 Feb 2022 23:57:00 GMThttps://www.pnas.org/doi/10.1073/pnas.1821323116Here, we report that the cystine/glutamate transporter xCT is essential for RAS-induced tumorigenicity by enhancing antioxidant glutathione synthesis. Our findings uncover that RAS controls xCT transcription by downstream activation of ETS-1 to synergize with ATF4.Wed, 17 Apr 2019 23:55:00 GMThttps://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/cbf.3581Studies have confirmed that xCT is highly expressed in a variety of tumour and is associated with tumour proliferation, invasion, metastasis, drug resistance and ferroptosis, and can be used as a potential target for tumour treatment.Fri, 05 Jun 2026 05:13:00 GMThttps://www.sciencedaily.com/releases/2024/03/240326103905.htmThe xCT protein, which plays an important role as a transport molecule in the cell, could play a part in cancer treatment in the future, researchers have discovered.Tue, 26 Mar 2024 16:16:00 GMT