The Lancet

Advances in understanding the impact of sex on kidney health and disease

Biological differences exist between males and females in kidney structure and function, leading to sex heterogeneity in the presentation and outcomes of chronic kidney disease (CKD) and response to ...

Life-changing benefits of hydroxyurea for sickle cell anemia affirmed by 10-year study

Fewer serious complications. Fewer hospitalizations and blood transfusions. Better growth and development. And a markedly ...
C&EN

Design and Synthesis of 2-(4-Bromophenyl)Quinoline-4-Carbohydrazide Derivatives via Molecular Hybridization as Novel Microbial DNA-Gyrase Inhibitors

Department of Chemistry, College of Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia Department of Chemistry, Faculty of Science, Sohag University, Sohag 82524, Egypt ...
PNAS

Natural mutations in a Staphylococcus aureus virulence regulator attenuate cytotoxicity but permit bacteremia and abscess formation

This effect is likely to be mediated in part via SSR 42, a long-noncoding RNA. We show that rsp controls SSR 42 expression, is induced by hydrogen peroxide, and is required for normal cytotoxicity and ...
Frontiers

Responses and adaptations of plants to abiotic stress: transcriptional regulation of secondary metabolic pathways, metabolomics, and nanobiological approaches

; Mishra et al., 2024 ). However, excessive accumulation of these heavy metals within plants causes harmful effects. Heavy metal toxicity elevates the oxidative stress in plants by decreasing the ...