Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

New simulator and computational tools generate realistic ‘virtual tissues’ and map cell-to-cell ‘conversations’ from spatial transcriptomics data, potentially accelerating AI-driven discoveries in ...

Inflammatory bowel disease (IBD) is an umbrella term for Crohn's disease and ulcerative colitis, which both involve chronic inflammation ... | Cell And Molecular Biology ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

The 10X Genomics Xenium Analyzer will support true single cell spatial transcriptomics on fresh frozen or fixed tissue samples. You can characterize 100s to 1000s of RNAs in cells and tissues using ...

Researchers in Nikolaus Rajewsky's lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to map a tumor's cellular neighborhoods in 3D and identify potential targets ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the ...

Exploring biology in its native environment is perhaps the ideal scenario for generating better hypotheses about the cellular interactions that influence—and drive—healthy and diseased states, ...

The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes. Traditional research methods, reliant on bulk ...