JA Rosenfeld is an employee of Signature Genomic Laboratories, a subsidiary of PerkinElmer, Inc. The authors have no other relevant affiliations or financial involvement with any organization or ...

Chromosomal microarray has been widely adopted as the first-tier clinical test for individuals with multiple congenital anomalies, developmental delay, intellectual disability, and autism spectrum ...

Anomalies detected with ultrasound in fetuses with normal karyotypes may be associated with unusual copy number variants (CNVs), a secondary analysis shows. Jennifer C. Donnelly, MD, from the ...

A large study from Children's Hospital Boston and the Boston-based Autism Consortium finds that a genetic test that samples the entire genome, known as chromosomal microarray analysis, has about three ...

Surveying a small group of women participating in a larger study investigating the use of DNA microarrays to identify the possibility of prenatal chromosomal abnormalities, researchers documented the ...

An elegant new study confirms that the most commonly used method of screening for embryo abnormalities following in vitro fertilization (IVF) does accurately predict the success of embryo ...

At present, when a woman undergoes preimplantation genetic screening (PGS) in a fertility clinic, doctors are trying to select an egg or an embryo that is healthy and doesn't have a chromosome ...

(HealthDay News) – Microarray analysis can be a useful addition to karyotyping in prenatal testing and appears to be helpful in the investigation of stillbirth, according to two studies published in ...

In each type of cell, like a muscle cell or a skin cell, different genes are expressed (turned on) or silenced (turned off). If the cells that are turned on mutate, they could—depending on what role ...